Reversible host cell surface remodelling limits immune recognition and maximizes transmission of Plasmodium falciparum gametocytes
P. Ngotho, K. Dantzler Press, M. Peedell, W. Muasya, B. R. Omondi, S. O. Otoboh, K. B. Seydel, M. Kapulu, M. Laufer, T. E. Taylor, T. Bousema, M. Marti
This study shows that surface remodelling in Plasmodium falciparum gametocytes helps evade immune detection and facilitates transmission by controlling their sequestration and release into the bloodstream.
bioRxiv · Apr 30, 2024 · PreprintMicrobiology