An Atlas of Phosphorylation and Proteolytic Processing Events During Excitotoxic Neuronal Death Reveals New Therapeutic Opportunities
S. S. Ameen, A. Dufour, M. I. Hossain, A. Hoque, S. Sturgeon, H. Nandurkar, D. Draxler, R. Medcalf, M. A. Kamaruddin, I. Lucet, M. Leeming, D. Liu, A. Dhillon, J. P. Lim, H. Zhu, , H. C. Cheng
The paper uses proteomic approaches to identify proteins modified during excitotoxic neuronal death and shows that blocking Src kinase protects neurons in a rat model.
bioRxiv · Jun 15, 2020 · PreprintBiochemistry