Author

I. Lucet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:rat· 1

Frequent Co-Authors

O. Patel· 2 shared A. Boussioutas· 1 shared A. Dhillon· 1 shared A. Dufour· 1 shared A. Hoque· 1 shared A. I. Azimpour· 1 shared A. Kropp· 1 shared A. L. Chand· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

O. Patel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

When two is a crowd - Structural mapping of PEAK pseudokinase interactions identifies 14 3 3 as a molecular switch for PEAK3/Crk signaling.

M. J. Roy, M. G. Surudoi, A. Kropp, J. Hou, W. Dai, J. M. Hardy, L.-Y. Liang, T. R. Cotton, B. C. Lechenberg, T. A. Dite, X. Ma, R. J. Daly, O. Patel, I. Lucet

The paper identifies 14-3-3 as a molecular switch for PEAK3/Crk signaling by mapping PEAK pseudokinase interactions and demonstrating a conserved high affinity 14-3-3 motif.

bioRxiv · Sep 1, 2022 · PreprintBiochemistry

The kinase activity of the cancer stem cell marker DCLK1 drives gastric cancer progression by reprogramming the stromal tumor landscape

S. Afshar-Sterle, A. L. E. Carli, R. O'Keefe, J. Tse, S. Fischer, A. I. Azimpour, D. Baloyan, L. Elias, P. Thilakasiri, O. Patel, F. M. Ferguson, M. F. Eissmann, A. L. Chand, N. S. Gray, R. Busuttil, , M. Buchert

This study identifies DCLK1 kinase activity as a driver of gastric cancer progression by reprogramming the tumor stroma and promoting invasiveness and metastasis.

bioRxiv · Apr 21, 2022 · PreprintCancer Biology

An Atlas of Phosphorylation and Proteolytic Processing Events During Excitotoxic Neuronal Death Reveals New Therapeutic Opportunities

S. S. Ameen, A. Dufour, M. I. Hossain, A. Hoque, S. Sturgeon, H. Nandurkar, D. Draxler, R. Medcalf, M. A. Kamaruddin, I. Lucet, M. Leeming, D. Liu, A. Dhillon, J. P. Lim, H. Zhu, , H. C. Cheng

The paper uses proteomic approaches to identify proteins modified during excitotoxic neuronal death and shows that blocking Src kinase protects neurons in a rat model.

bioRxiv · Jun 15, 2020 · PreprintBiochemistry