ImmunologybioRxiv
A minimal RNA ligand for potent RIG-I activation in living mice
M. M. Linehan, T. H. Dickey, E. S. Molinari…·A. M. Pyle
This study develops synthetic RNA ligands that activate RIG-I in mice, inducing interferon responses and specific gene expression, and shows their potential as therapeutic tools.
DOI 10.1126/sciadv.1701854