Author

M. M. Soniat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

I. J. Finkelstein· 3 shared G. Nguyen· 1 shared H.-C. Kuo· 1 shared J. M. Schaub· 1 shared L. R. Myler· 1 shared T. T. Paull· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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3 shared papersBiophysics

I. J. Finkelstein

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintJul 1, 2022

MRN and Topoisomerase IIIα-RMI1/2 synchronize DNA resection motor proteins

M. M. Soniat, G. Nguyen, H.-C. Kuo, I. J. Finkelstein

This study uses single-molecule imaging to show how MRN and TOP3A-RMI1/2 coordinate with BLM and DNA2 to efficiently resect DNA during homologous recombination.

DOI 10.1101/2022.07.01.498452

experimental assaychromatin & epigenetic regulation

𝕏 PostBluesky

BiophysicsbioRxivJun 3, 2021

Polymerase theta-helicase promotes end joining by stripping single-stranded DNA-binding proteins and bridging DNA ends

J. M. Schaub, M. M. Soniat, I. J. Finkelstein

This study shows that Pol{theta}-helicase removes RPA and RAD51 from ssDNA and bridges DNA ends to facilitate TMEJ.

DOI 10.1093/nar/gkac119

experimental assay

𝕏 PostBluesky

BiophysicsbioRxivJan 17, 2019

RPA phosphorylation regulates DNA resection

M. M. Soniat, L. R. Myler, T. T. Paull, I. J. Finkelstein

This study identifies RPA phosphorylation as a mechanism that limits DNA resection by regulating BLM helicase activity in human cells.

DOI 10.1016/j.molcel.2019.05.005

humanDNA methylation

𝕏 PostBluesky