Author

J. M. Schaub

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

I. J. Finkelstein· 3 shared A. Dzifa· 1 shared A. G.-W. Lee· 1 shared A. M. DiVenere· 1 shared A. W. Nguyen· 1 shared C. K. Hjorth· 1 shared C.-L. Hsieh· 1 shared C.-W. Chou· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBiophysics

I. J. Finkelstein

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3 papers

Recent·Most cited

BiophysicsbioRxivJun 3, 2021

Polymerase theta-helicase promotes end joining by stripping single-stranded DNA-binding proteins and bridging DNA ends

J. M. Schaub, M. M. Soniat, I. J. Finkelstein

This study shows that Pol{theta}-helicase removes RPA and RAD51 from ssDNA and bridges DNA ends to facilitate TMEJ.

DOI 10.1093/nar/gkac119

experimental assay

𝕏 PostBluesky

MicrobiologybioRxivMay 30, 2020

Structure-based Design of Prefusion-stabilized SARS-CoV-2 Spikes

C.-L. Hsieh, J. A. Goldsmith, J. M. Schaub…·J. S. McLellan

This study designs and characterizes prefusion-stabilized SARS-CoV-2 spike variants to improve protein yield and stability for vaccine and diagnostic development.

DOI 10.1126/science.abd0826

cryo-EMexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivMay 15, 2020

RADX condenses single-stranded DNA to antagonize RAD51 loading

H. Zhang, J. M. Schaub, I. J. Finkelstein

This study shows RADX condenses single-stranded DNA and blocks RAD51 loading, revealing its role in regulating DNA replication and repair.

DOI 10.1093/nar/gkaa559

humanDNA methylation

𝕏 PostBluesky