Cancer BiologybioRxiv
The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma
K. Ponnusamy, M. M. Tzioni, M. Begum…·A. Karadimitris
The paper shows that the ZBP1-IRF3 axis promotes myeloma cell proliferation by activating cell cycle genes instead of type I IFN responses.
DOI 10.3324/haematol.2020.274480