G. Schwarz

Novel, postnatal manifestation of an epidermal barrier defect in a mouse model of isolated sulfite oxidase deficiency

This study identifies a postnatal skin barrier defect in Suox-/- mice, linking sulfite oxidase deficiency to epidermal dysfunction and early mortality.

Sulfite oxidase deficiency causes persulfidation loss and H2S release

This study shows that SOX deficiency leads to persulfidation loss and increased H2S release, with thiosulfate accumulation and metabolic rewiring in a mouse model.

Parallel Activation of Src and Hif1α Increases Localized Glycolytic ATP Generation for Re-assembly of Endothelial Adherens Junctions

This study shows that Src and Hif1α activation increases glycolytic ATP production near endothelial adherens junctions, facilitating their re-assembly after injury.

Pentameric assembly of glycine receptor intracellular domains provides insights into gephyrin clustering

The paper studies glycine receptor intracellular domains using a pentameric scaffold, revealing structural flexibility and a mechanism for gephyrin clustering at inhibitory synapses.

A systematic analysis of diet-induced nephroprotection reveals overlapping and conserved changes in cysteine catabolism

This study compares six dietary regimens to identify their protective effects against kidney injury and finds overlapping metabolic changes in cysteine catabolism across diets.

Glycolysis Inhibition Regulates Endothelial Junctions by Perturbing Actin and Focal Adhesions

This study shows that glycolysis inhibition reduces VE-cadherin junction tension by disrupting actin and focal adhesions, impacting endothelial barrier integrity.