Author

M. Masureel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

B. K. Kobilka· 2 shared A. ElSohly· 1 shared A. Inoue· 1 shared B. Barsi-Rhyne· 1 shared C. Mullen· 1 shared C. Tsai· 1 shared D. DiCara· 1 shared D. H. Siepe· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

B. K. Kobilka

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Author profile →

3 papers

Recent·Most cited

Exposing the molecular heterogeneity of glycosylated biotherapeutics

L. F. Schachner, C. Mullen, W. Phung, J. D. Hinkle, M. I. Beardsley, T. Bentley, P. Day, C. Tsai, S. Sukumaran, T. Baginski, D. DiCara, N. Agard, M. Masureel, J. Gober, A. ElSohly, , W. Sandoval

This paper introduces a new method for analyzing glycoform heterogeneity in biotherapeutics using mass spectrometry and bioinformatics, showing its effectiveness in measuring proteoform diversity and correlating glycoform sub-populations with pharmacological properties.

bioRxiv · May 10, 2023Biochemistry

Membrane phosphoinositides stabilize GPCR-arrestin complexes and offer temporal control of complex assembly and dynamics

J. Janetzko, R. Kise, B. Barsi-Rhyne, D. H. Siepe, F. M. Heydenreich, M. Masureel, K. Kawakami, K. C. Garcia, M. Von Zastrow, A. Inoue, B. K. Kobilka

This study identifies membrane phosphoinositides as regulators of GPCR-arrestin complex dynamics, showing they stabilize complexes and enable temporal control of receptor signaling and recycling.

bioRxiv · Oct 9, 2021Biochemistry

Local membrane charge regulates β2 adrenergic receptor coupling to Gi

M. J. Strohman, S. Maeda, D. Hilger, M. Masureel, Y. Du, B. K. Kobilka

This study shows that local membrane charge affects β2AR coupling to Gi and Gs proteins, with negative charges inhibiting Gi coupling and promoting Gs coupling.

bioRxiv · Aug 25, 2018Biochemistry