Author

M. Mercadante

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

E. R. Kastenhuber· 2 shared J. L. Johnson· 2 shared L. C. Cantley· 2 shared F. Muecksch· 1 shared G. R. Whittaker· 1 shared J. A. Jaimes· 1 shared R. E. Schwartz· 1 shared T. M. Yaron· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMicrobiology

E. R. Kastenhuber

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJun 16, 2022

Evolution of host protease interactions among SARS-CoV-2 variants of concern and related coronaviruses

E. R. Kastenhuber, M. Mercadante, J. L. Johnson…·L. C. Cantley

The paper examines how SARS-CoV-2 variants interact with host proteases and shows that some proteases remain effective against variant spike proteins.

DOI 10.1101/2022.06.16.496428

humanproteomics

𝕏 PostBluesky

MicrobiologybioRxivMar 31, 2021

Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry

E. R. Kastenhuber, J. A. Jaimes, J. L. Johnson…·L. C. Cantley

This study shows coagulation factors like factor Xa and thrombin directly cleave SARS-CoV-2 spike, enhancing viral entry, and suggests anticoagulation could reduce infection.

DOI 10.7554/elife.77444

humanexperimental assay

𝕏 PostBluesky