The X-linked splicing regulator MBNL3 has been co-opted to restrict placental growth in eutherians
T. Spruce, M. Plass, A. Gohr, D. Ray, M. Martinez de Lagran, G. Rot, A. Novoa, D. Burguera, J. Permanyer, M. Miret, H. Zheng, M. Swanson, Q. Morris, M. Mallo, M. Dierssen, , M. Irimia
This study identifies Mbnl3 as a placenta-specific X-linked gene that restricts placental growth in eutherians through altered RNA binding specificities and novel biological functions.
bioRxiv · Sep 8, 2021Evolutionary Biology