The dual character of the inhibitory functions of CD6
R. F. Santos, A. De Sousa Linhares, M. S. Cardoso, A. Novoa, H. Luche, F. Gartner, B. Malissen, P. Steinberger, S. Davis, M. Mallo, L. Oliveira, A. M. Carmo
This study investigates CD6's dual inhibitory and costimulatory functions, showing it suppresses T cell responsiveness via its cytoplasmic domain and modulates autoimmunity through extracellular interactions.
bioRxiv · Apr 29, 2022 · PreprintImmunology