Author

Q. Morris

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:clustering· 3 Approach:deep learning· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:whole-genome sequencing· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Ang Houle· 1 shared A. Gohr· 1 shared A. Novoa· 1 shared A. Shkurin· 1 shared B. J. Andrews· 1 shared B. Lin· 1 shared B. Pernaute· 1 shared C. Boone· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

A. Ang Houle

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Author profile →

5 papers

Recent·Most cited

Inferring cancer type-specific patterns of metastatic spread using Metient

D. Koyyalagunta, K. Ganesh, Q. Morris

Metient infers cancer type-specific metastatic spread patterns using gradient-based optimization, revealing new insights into metastasis mechanisms and treatment strategies.

bioRxiv · Jul 9, 2024Cancer Biology

Regional mutational signature activities in cancer genomes

C. Timmons, Q. Morris, C. F. Harrigan

This study identifies regional changes in mutational signature activities across cancer genomes, revealing recurrent changepoints that may reflect evolutionary and epigenetic factors.

bioRxiv · Jan 23, 2022Cancer Biology

The X-linked splicing regulator MBNL3 has been co-opted to restrict placental growth in eutherians

T. Spruce, M. Plass, A. Gohr, D. Ray, M. Martinez de Lagran, G. Rot, A. Novoa, D. Burguera, J. Permanyer, M. Miret, H. Zheng, M. Swanson, Q. Morris, M. Mallo, M. Dierssen, , M. Irimia

This study identifies Mbnl3 as a placenta-specific X-linked gene that restricts placental growth in eutherians through altered RNA binding specificities and novel biological functions.

bioRxiv · Sep 8, 2021Evolutionary Biology

Interacting evolutionary pressures drive mutation dynamics and health outcomes in aging blood

K. Skead, A. Ang Houle, S. Abelson, M. Agbessi, V. Bruat, B. Lin, D. Soave, L. Shlush, S. Wright, J. Dick, Q. Morris, P. Awadalla

The paper models positive and negative selection in blood cells to explain why some people with ARCH do not progress to AML, finding that passenger mutation burden influences clonal dominance.

Nature Communications · Aug 13, 2021Peer-reviewedCancer Biology

Exploring endocytic compartment morphology with systematic genetics and single cell image analysis

M. Mattiazzi Usaj, N. Sahin, H. Friesen, C. Pons, M. Usaj, M. Paz Masinas, E. Shuteriqi, A. Shkurin, P. Aloy, Q. Morris, C. Boone, B. J. Andrews

The paper uses systematic genetics and single-cell image analysis to identify genes affecting endocytic compartment morphology in yeast, revealing pleiotropy and cellular heterogeneity.

bioRxiv · Aug 4, 2019Cell Biology