Author

M. Moorghen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

L. M. Wang· 2 shared A. Antoniou· 1 shared A. Banerjee· 1 shared A. Lorincz· 1 shared A. M. Berner· 1 shared A.-M. Baker· 1 shared B. Lu· 1 shared C. James· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

L. M. Wang

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2 papers

Recent·Most cited

Colorectal cancer risk in bowel adenomas based on lifestyle exposures, tissue preconditioning and DNA methylation

J. Sutton, M. Moorghen, L. M. Wang, C. Thirlwell, C. Pipinikas, A. Lorincz

This study identifies DNA methylation changes linked to high alcohol and BMI exposures in colorectal adenomas, suggesting they may increase CRC risk through tissue preconditioning.

bioRxiv · Aug 26, 2021 · PreprintCancer Biology

Negative selection may cause grossly altered but broadly stable karyotypes in metastatic colorectal cancer

W. Cross, S. Nowinski, G. Cresswell, M. Mossner, A. Banerjee, B. Lu, M. Williams, G. Vlachogiannis, L. Gay, A.-M. Baker, C. Kimberley, F. Whiting, H. Belnoue-Davis, P. Martinez, M. Traki, , Wat

This study analyzes longitudinal genomic data from colorectal cancer patients to show that negative selection stabilizes karyotypes during tumor progression and metastasis.

bioRxiv · Mar 26, 2020 · PreprintCancer Biology