Cell BiologybioRxivPreprint
Progressive protein aggregation in PRPF31 patient retinal pigment epithelium cells: the mechanism and its reversal through activation of autophagy
M. Georgiou, C. Yang, R. Atkinson…·M. Lako
This study shows that PRPF31 mutations cause progressive protein aggregation in RPE cells, which can be reversed by autophagy activation.
DOI 10.1101/2021.10.11.463925