Author

M. Lako

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Collin· 2 shared L. Armstrong· 2 shared M. Georgiou· 2 shared A. Buskin· 1 shared A. Shukurov· 1 shared A. W. Baggaley· 1 shared B. Vernon· 1 shared B. Wagner· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

J. Collin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Conjunctival epithelial cells resist productive SARS-CoV-2 infection

M. Lako, R. M. Jackson, C. F. Hatton, J. S. Spegarova, M. Georgiou, J. Collin, E. Stephenson, B. Vernon, I. J. Haq, R. Hussain, J. M. Coxhead, H. S. Mudhar, B. Wagner, M. Hasoon, T. Davie, , C. J. Duncan

The paper investigates whether conjunctival epithelial cells can be infected by SARS-CoV-2 and finds that while genome expression occurs, productive infection does not.

bioRxiv · Dec 20, 2021Cell Biology

Progressive protein aggregation in PRPF31 patient retinal pigment epithelium cells: the mechanism and its reversal through activation of autophagy

M. Georgiou, C. Yang, R. Atkinson, K.-T. Pan, A. Buskin, M. Moya Molina, J. Collin, J. Al-Aama, F. Goertler, S. E. J. Ludwig, T. Davey, R. Luhrmann, S. Nagaraja-Grellscheid, C. Johnson, R. Ali, , M. Lako

This study shows that PRPF31 mutations cause progressive protein aggregation in RPE cells, which can be reversed by autophagy activation.

bioRxiv · Oct 11, 2021 · PreprintCell Biology

Spatio-temporal analyses of OCT4 expression and fate transitions in human embryonic stem cells

S. Orozco-Fuentes, L. E. Wadkin, I. Neganova, M. Lako, R. A. Barrio, A. W. Baggaley, A. Shukurov, N. G. Parker

The paper analyzes OCT4 expression dynamics and fate transitions in human embryonic stem cells under BMP4 treatment, showing dynamic expression patterns and clustering behavior.

Physical Biology · Feb 16, 2021Peer-reviewedBiophysics