Author

M. Murillo-Leon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

T. Steinfeldt· 3 shared G. A. Taylor· 2 shared A. F. Arenas Soto· 1 shared A. M. Bastidas Quintero· 1 shared A. M. Bastidas-Quintero· 1 shared A. Ohnemus· 1 shared B. Saller· 1 shared C. Campos· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersMicrobiology

T. Steinfeldt

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dual role of Toxoplasma gondii ROP5 and ROP18 for NLRP3 inhibition

M. Murillo-Leon, A. M. Bastidas Quintero, S. Singh, X. Mueller, O. Gorka, B. Saller, A. F. Arenas Soto, C. Campos, J. E. Gomez-Marin, O. Gross, K. Pfeffer, J. C. Howard, G. A. Taylor, T. Steinfeldt

This paper identifies vacuolar disruption as a trigger for NLRP3 inflammasome activation in Toxoplasma gondii infection and shows ROP5 and ROP18 inhibit IL-1β release by protecting the parasitophorous vacuole and interacting with GBP5.

bioRxiv · Sep 17, 2023 · PreprintMicrobiology

IFN-lambda is protective against lethal oral Toxoplasma gondii infection

M. Murillo-Leon, A. M. Bastidas-Quintero, N. S. Endres, D. Schnepf, E. Delgado-Betancourt, A. Ohnemus, G. A. Taylor, M. Schwemmle, P. Staeheli, T. Steinfeldt

This study shows that IFN-lambda protects against lethal oral Toxoplasma gondii infection by enhancing intestinal epithelial and neutrophil responses.

bioRxiv · Feb 24, 2023 · PreprintImmunology

In vitro maturation of Toxoplasma gondii bradyzoites in human myotubes and their metabolomic characterization

C. Christiansen, D. Maus, E. Hoppenz, F. Melerowicz, J. Scholz, M. Murillo-Leon, T. Steinfeldt, T. Hoffmann, F. Seeber, M. Blume

This study develops an in vitro model of mature Toxoplasma gondii bradyzoite cysts in human myotubes and characterizes their metabolomic profile.

bioRxiv · Jan 15, 2021Microbiology