Author

M. Nick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:C. elegans· 1 Organism:mouse· 1

Frequent Co-Authors

D. B. Sattelle· 2 shared F. A. Partridge· 2 shared A. Coghlan· 1 shared A. E. Brown· 1 shared A. J. Russell· 1 shared C. Brandt· 1 shared C. J. R. Bataille· 1 shared C. McCarthy· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

D. B. Sattelle

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A drug repurposing screen for whipworms informed by comparative genomics

A. Coghlan, F. A. Partridge, M. A. Duque-Correa, G. Rinaldi, S. Clare, L. Seymour, C. Brandt, T. T. Mkandawire, C. McCarthy, N. Holroyd, M. Nick, A. E. Brown, S. Tonitiwong, D. B. Sattelle, M. Berriman

This paper identifies potential anti-whipworm drugs by testing approved human drugs ex vivo and in vivo, finding limited efficacy due to pharmacokinetic challenges.

bioRxiv · Mar 2, 2023Pharmacology & Toxicology

Screening the Medicines for Malaria Pandemic Response Box chemical library on Caenorhabditis elegans identifies re-profiled candidate anthelmintic drug leads

M. Nick, F. A. Partridge, R. Forman, C. J. R. Bataille, K. J. Else, A. J. Russell, D. B. Sattelle

The paper screens a chemical library on C. elegans to identify potential anthelmintic drug leads effective against parasitic nematodes.

bioRxiv · Aug 10, 2022 · PreprintPharmacology & Toxicology