Pharmacology & ToxicologybioRxiv
A drug repurposing screen for whipworms informed by comparative genomics
A. Coghlan, F. A. Partridge, M. A. Duque-Correa…·M. Berriman
This paper identifies potential anti-whipworm drugs by testing approved human drugs ex vivo and in vivo, finding limited efficacy due to pharmacokinetic challenges.
DOI 10.1371/journal.pntd.0011205