Author

M. Nowinska

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Possenti· 2 shared M. Vendruscolo· 2 shared R. I. Horne· 2 shared R. Staats· 2 shared S. Chia· 2 shared T. P. J. Knowles· 2 shared Z. F. Brotzakis· 2 shared A. Aubert· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiophysics

A. Possenti

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2 papers

Recent·Most cited

BiophysicsMolecular PharmaceuticsPeer-reviewedNov 14, 2022

Structure-based discovery of small molecule inhibitors of the autocatalytic proliferation of alpha-synuclein aggregates

S. Chia, Z. F. Brotzakis, R. I. Horne…·M. Vendruscolo

This study identifies small molecules that inhibit alpha-synuclein aggregate proliferation using structure-based and kinetic assays.

DOI 10.1021/acs.molpharmaceut.2c00548

humanproteomics

𝕏 PostBluesky

BiophysicsbioRxivNov 10, 2021

Discovery of Potent Inhibitors of α-Synuclein Aggregation Using Structure-Based Iterative Learning

R. I. Horne, E. Andrzejewska, P. Alam…·M. Vendruscolo

This paper uses structure-based machine learning to identify potent small molecule inhibitors of α-synuclein aggregation, achieving compounds two orders of magnitude more potent than previous reports.

DOI 10.1038/s41589-024-01580-x

deep learningdrug response / drug discovery

𝕏 PostBluesky