Author

M. Paloni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 3 Approach:statistical model· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:protein structure prediction· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. Barducci· 6 shared A. Ancelin· 1 shared A. Boulahtouf· 1 shared A. Constantinou· 1 shared A. Hessel· 1 shared A. R. Finney· 1 shared A. Takedachi· 1 shared C. Bechara· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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6 shared papersBiophysics

A. Barducci

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Nucleation of Biomolecular Condensates from Finite-Sized Simulations

L. Li, M. Paloni, A. R. Finney, A. Barducci, M. Salvalaglio

This paper presents a method to estimate thermodynamic and kinetic parameters of protein condensates from finite-sized simulations, showing differences in nucleation behavior between NDDX4 and FUS-LC.

bioRxiv · Nov 11, 2022Biophysics

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair

E. Alghoul, M. Paloni, A. Takedachi, S. Urbach, A. Barducci, P.-H. L. Gaillard, J. Basbous, A. Constantinou

This study shows SLX4 forms membraneless compartments that regulate SUMO-RNF4 pathway activity and DNA repair processes.

bioRxiv · Sep 20, 2022Biochemistry

Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex

J. Gruszczyk, L. Grandvuillemin, J. Lai-Kee-Him, M. Paloni, C. G. Savva, P. Germain, M. Grimaldi, A. Boulahtouf, H.-S. Kwong, J. Bous, A. Ancelin, C. Bechara, A. Barducci, P. Balaguer, W. Bourguet

The paper presents a cryo-EM structure of the AHR complex bound to a ligand, revealing structural details of its activation mechanism and ligand-binding specificity.

bioRxiv · May 17, 2022Biochemistry

Functional control of a 0.5 MDa TET aminopeptidase by a flexible loop revealed by MAS NMR

D. F. Gauto, P. Macek, D. Malinverni, H. Fraga, M. Paloni, I. Sucec, A. Hessel, J. P. Bustamante, A. Barducci, P. Schanda

The paper uses MAS NMR and computational methods to show a flexible loop in TET2 aminopeptidase is critical for catalytic function and substrate processing.

bioRxiv · Jun 29, 2021Biophysics

Arginine multivalency stabilizes protein/RNA condensates

M. Paloni, G. Bussi, A. Barducci

This study uses molecular dynamics simulations to show that arginine stabilizes protein/RNA condensates more effectively than lysine due to its multivalency.

bioRxiv · Apr 22, 2021Biophysics

Unraveling molecular interactions in a phase-separating protein by atomistic simulations

M. Paloni, R. Bailly, L. Ciandrini, A. Barducci

This study uses atomistic simulations to investigate molecular interactions driving phase separation in the N-terminal disordered region of DEAD-box helicase 4.

bioRxiv · May 16, 2020Biophysics