A lncRNA/Lin28/Let7 Axis Coupled To DNA Methylation Fine Tunes The Dynamics Of A Cell State Transition
M. A. Li, P. P. Amaral, P. Cheung, J. H. Bergmann, M. Kinoshita, T. Kalkan, M. Ralser, S. Robson, F. von Meyenn, M. Paramor, F. Yang, C. Chen, J. Nichols, D. L. Spector, T. Kouzarides, , A. Smith
The paper identifies a lncRNA/miRNA/DNA methylation axis that regulates the timing of stem cell state transition from naive pluripotency.
bioRxiv · Apr 26, 2017Cell Biology