PhysiologybioRxiv
Hepatocyte Membrane Potential Regulates Serum Insulin and Insulin Sensitivity by Altering Hepatic GABA Release
C. E. Geisler, S. Ghimire, C. Hepler…·B. J. Renquist
This study identifies GABA as a novel hepatokine dysregulated in obesity, showing that hepatic GABA release affects serum insulin and insulin sensitivity.
DOI 10.1016/j.celrep.2021.109298