Cancer BiologybioRxivPreprint
Functional plasticity and reversible growth behavior of patients acute myeloid leukemia stem cells growing in mice
S. Ebinger, C. Zeller, M. Carlet…·I. Jeremias
This study shows AML stem cells can switch between low-cycling, treatment-resistant and actively proliferating states in mice, suggesting functional plasticity that could be targeted therapeutically.
DOI 10.1101/707935