Cancer BiologybioRxivPreprint
IL-1β promotes MPN disease initiation by favoring early clonal expansion of JAK2-mutant hematopoietic stem cells
S. Rai, Y. Zhang, E. Grockowiak…·R. C. Skoda
This study shows IL-1β promotes MPN initiation by enhancing early clonal expansion of JAK2-mutant HSCs in a mouse model.
DOI 10.1101/2023.05.21.541610