PhysiologybioRxivPreprint
Late-life isoleucine restriction promotes physiological and molecular signatures of healthy aging
C.-Y. Yeh, L. C. S. Chini, J. W. Davidson…·D. Lamming
This study shows that reducing amino acids or isoleucine in the diet of aged mice improves metabolic health, reduces frailty, and slows aging markers.
DOI 10.1101/2023.02.06.527311