ImmunologybioRxiv
Efficient formation and maintenance of humoral and CD4 T cell immunity targeting the viral capsid in acute-resolving hepatitis E infection
B. Csernalabics, M. S. Marinescu, L. Maurer…·T. Boettler
The paper longitudinally characterizes HEV-specific CD4 T cells and neutralizing antibodies targeting nHEV and eHEV in acute and resolved HEV infection, finding capsid-specific immunity dominates and correlates with nAb responses.
DOI 10.1016/j.jhep.2023.12.016