M. S. Zeden

This study shows that mutating the pentose phosphate pathway gene pgl in MRSA increases resistance to beta-lactam antibiotics through metabolic reprogramming and changes in cell envelope precursors.

This study shows that purine nucleosides like guanosine and xanthosine reduce β-lactam resistance in MRSA by lowering c-di-AMP levels, acting as adjuvants to restore antibiotic effectiveness.

This study shows that mutating lspA or inhibiting LspA with globomycin increases MRSA resistance to beta-lactam antibiotics by affecting cell envelope components beyond peptidoglycan.

This study identifies glutamine and glutamate transporters in S. aureus and shows their impact on c-di-AMP production and growth in rich medium.

This study identifies c-di-AMP's role in osmotic regulation in S. aureus but shows it is not required for anaerobic growth.