MicrobiologybioRxivPreprint
Purine nucleosides interfere with c-di-AMP levels and act as adjuvants to re-sensitize MRSA to β-lactam antibiotics
A. Nolan, M. S. Zeden, C. Campbell…·J. P. O'Gara
This study shows that purine nucleosides like guanosine and xanthosine reduce β-lactam resistance in MRSA by lowering c-di-AMP levels, acting as adjuvants to restore antibiotic effectiveness.
DOI 10.1101/2022.09.01.506298