Biochemical and structural analysis reveals the Neurofibromin (NF1) protein forms a high-affinity dimer
M. Sherekar, S.-W. Han, R. Ghirlando, S. Messing, M. Drew, P. Juneja, H. O'Neill, C. Stanley, D. Bhowmik, A. Ramanathan, S. Subramaniam, D. V. Nissley, W. Gillette, F. McCormick, D. Esposito
This study shows Neurofibromin forms a high-affinity dimer through biochemical and structural analysis, with implications for its function in RAS-MAPK signaling.
bioRxiv · Sep 5, 2019 · PreprintBiochemistry