Cell BiologybioRxivPreprint
OTUD1 deubiquitylase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways
D. Oikawa, M. Gi, H. Kosako…·F. Tokunaga
This study identifies OTUD1 as a deubiquitylase that suppresses NF-κB and KEAP1-mediated inflammatory and oxidative stress responses, while promoting antiviral pathways and ROS-associated cell death.
DOI 10.1101/2021.12.26.474226