Author

M. T. Wright

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

L. Plate· 4 shared B. I. Reinfeld· 1 shared B. J. Reisman· 1 shared B. O. Bachmann· 1 shared B. Timalsina· 1 shared C. Sanders· 1 shared C. V. Robinson· 1 shared D. R. Heintzman· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersCell Biology

L. Plate

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Time-Resolved Interactome Profiling Deconvolutes Secretory Protein Quality Control Dynamics

M. T. Wright, B. Timalsina, V. A. G. Lopez, J. N. Hermanson, S. Garcia, L. Plate

This study develops TRIP, a mass-spectrometry method to map protein interactions over time, and applies it to study hypothyroidism by analyzing thyroglobulin interactions and identifying VCP and TEX264 as key factors in protein degradation.

bioRxiv · Sep 4, 2022Cell Biology

Multi-marker metabarcoding resolves subtle variations in freshwater condition: Bioindicators, ecological traits, and trophic interactions

C. V. Robinson, T. M. Porter, V. C. Maitland, M. T. Wright, M. Hajibabaei

This study uses DNA metabarcoding to assess freshwater ecological condition by analyzing taxonomic and trophic diversity across sites with varying habitat quality.

bioRxiv · Nov 14, 2021Ecology

A Family of Glycosylated Macrolides Selectively Target Energetic Vulnerabilities in Leukemia

B. J. Reisman, H. Guo, H. E. Ramsey, M. T. Wright, B. I. Reinfeld, P. B. Ferrell, G. A. Sulikowski, W. K. Rathmell, M. R. Savona, L. Plate, J. L. Rubinstein, B. O. Bachmann

This study identifies the mitochondrial ATP synthase as the target of apoptolidin family glycomacrolides and demonstrates their efficacy in suppressing leukemia progression.

bioRxiv · May 31, 2021Biochemistry

Glycosylation Limits Forward Trafficking of the Tetraspan Membrane Protein PMP22

J. T. Marinko, M. T. Wright, D. R. Heintzman, L. Plate, C. Sanders

The paper shows that N-linked glycosylation limits PMP22 cell surface trafficking and identifies key quality control factors in its biogenesis.

bioRxiv · Dec 18, 2020Cell Biology

Thyroglobulin Interactome Profiling Uncovers Molecular Mechanisms of Thyroid Dyshormonogenesis

M. T. Wright, L. Kouba, L. Plate

The paper identifies proteostasis network interactions affecting Tg processing and reveals mutation-specific changes in N-glycosylation components for degradation.

bioRxiv · Apr 8, 2020 · PreprintCell Biology