Cancer BiologybioRxivPreprint
Activation of the TRIF pathway and downstream targets results in the development of precancerous lesions during infection with Helicobacter.
P. Bali, I. Lozano-Pope, J. Hernandez…·M. Obonyo
This study shows that activation of the TRIF pathway and downstream IFN-I signaling promotes H. felis-induced gastric disease progression and is linked to poor survival in gastric cancer.
DOI 10.1101/2023.06.04.543598