M. V. Sefton

This study shows that methacrylic acid-based biomaterials promote peripheral nerve growth in mice through Igf-1 and Shh signaling, enhancing nociception and neuronal marker expression in a diabetic model.

This paper develops a biomaterial-based method to pre-vascularize the subcutaneous space for islet transplantation, enabling normoglycemia in diabetic mice and rats with reduced islet mass.