Cancer BiologybioRxivPreprint
Comparative Molecular Genomic Analyses of a Spontaneous Rhesus Macaque Model of Mismatch Repair-Deficient Colorectal Cancer
N. Ozirmak Lermi, S. B. Gray, C. M. Bowen…·E. Vilar
This study characterizes a spontaneous MMRd CRC model in rhesus macaques, finding high MSI levels and gene expression patterns similar to human CRC, supporting their use as an animal model.
DOI 10.1101/2021.08.19.456691