P. Tripathi

Chemically induced in vivo retinal neuron regeneration rescues vision in mice

This study identifies a small molecule cocktail that reprograms Muller glia into retinal neurons, restoring vision in mice with RGC injury.

In Silico Improvement of Highly Protective Anti-Malarial Antibodies

The paper improves an anti-malarial antibody using an in silico pipeline, resulting in a variant with higher binding affinity and better malaria protection.

MOV10 facilitates messenger RNA decay in an N6-methyladenosine (m6A) dependent manner to maintain the mouse embryonic stem cells state

The paper identifies MOV10 as a new m6A-reader that facilitates mRNA decay via m6A to regulate the WNT/β-CATENIN pathway and maintain mouse embryonic stem cell state.

Voltage-driven polyelectrolyte complexation inside a nanopore

This paper investigates how oppositely charged macromolecules form polyelectrolyte complexes inside a nanopore under an electric field, revealing distinct ionic current signatures and a four-step mechanism for complexation.

Electrical Unfolding of Cytochrome c During Translocation Through a Nanopore Constriction

This paper investigates how electric fields affect the translocation of cytochrome c through nanopores of different diameters, showing that electric fields can stabilize unfolded states and influence translocation modes.

Reticulocyte Infection Leads to Altered Behaviour, Drug Sensitivity and Host Cell Remodelling by Plasmodium falciparum.

This paper shows that Plasmodium falciparum infects reticulocytes with higher affinity, alters drug sensitivity, and remodels host cells through transcriptomic changes.

T-DNA integration is rapid and influenced by the chromatin state of the host genome.

The paper maps T-DNA integration sites in plants over time and finds uniform distribution with local biases and chromatin state influences.