M.-D. Phan

Molecular mechanisms of re-emerging chloramphenicol susceptibility in extended-spectrum beta-lactamase producing Enterobacterales

The paper investigates the re-emerging chloramphenicol susceptibility in ESBL-producing Enterobacterales by analyzing genotype-phenotype discordance and molecular mechanisms.

The T Cell Receptor beta Chain Repertoire of Tumor Infiltrating Lymphocytes Improves Neoantigen Prediction and Prioritization

This paper develops a machine learning model that integrates TCRβ and pHLA binding data to improve neoantigen prioritization in colorectal cancer, showing better performance than existing tools.

Improvement in Neoantigen Prediction via Integration of RNA Sequencing Data for Variant Calling

This study improves neoantigen prediction by integrating RNA sequencing data with DNA sequencing to identify more immunogenic neoantigens in colorectal cancer patients.

Fitness effects of CTX-M-15-encoding IncF plasmids on their native Escherichia coli ST131 H30Rx hosts

This study examines the fitness effects of CTX-M-15-encoding IncF plasmids in E. coli ST131 H30Rx hosts, finding moderate fitness costs in some strains but not others.

Modified defence peptides from horseshoe crab target and kill bacteria inside host cells

This study identifies modified antimicrobial peptides from horseshoe crabs that effectively kill bacteria, including UPEC, both extracellularly and intracellularly, with reduced toxicity to mammalian cells.

A new massively-parallel transposon mutagenesis approach comparing multiple datasets identifies novel mechanisms of action and resistance to triclosan

This paper introduces a new TraDIS approach with AlbaTraDIS tool to analyze triclosan resistance mechanisms across multiple concentrations, identifying novel genes involved in bacterial survival.