M. Whelan

Disease-attenuated pneumococcal biosynthesis gene mutants invade the mucosal epithelium and induce innate immunity

This paper shows that disease-attenuated pneumococcal mutants retain epithelial microinvasion but show reduced transmigration and altered inflammatory responses.

A versatile automated high-throughput drug screening platform for zebrafish embryos

The paper develops an automated high-throughput drug screening platform for zebrafish embryos using AI-driven image analysis and validation through GFP-tagged cell counts and genetic mutation assessments.

Assessments of hepatitis B virus-like particles and Crm197 as carrier proteins in melioidosis glycoconjugate vaccines

This study compares the effectiveness of Crm197 and hepatitis B virus-like particles as carrier proteins for a melioidosis glycoconjugate vaccine, finding that Crm197 conjugates produce higher antibody titres but both protect against bacterial challenge.