Author

R. Ragazzini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Assay:metagenomics· 2 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

P. Bonfanti· 3 shared C. Jolly· 2 shared A. Filby· 1 shared A. Fuller· 1 shared A. H. Patel· 1 shared A. L. Wilbrey-Clark· 1 shared A.-K. Reuschl· 1 shared C. Dominguez Conde· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

P. Bonfanti

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Disease-attenuated pneumococcal biosynthesis gene mutants invade the mucosal epithelium and induce innate immunity

C. M. Weight, G. M. Pollara, M. Betts, R. Ragazzini, M. Connor, E. Ramos-Sevillano, J. Reine, M. Whelan, J. A. Guerra-Assuncao, P. Bonfanti, C. Jolly, M. Noursadeghi, D. Ferreira, J. Brown, R. S. Heyderman

This paper shows that disease-attenuated pneumococcal mutants retain epithelial microinvasion but show reduced transmigration and altered inflammatory responses.

bioRxiv · Jun 15, 2023Microbiology

Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants

A.-K. Reuschl, L. G. Thorne, M. X. V. Whelan, R. Ragazzini, W. Furnon, V. M. Cowton, G. de Lorenzo, D. Mesner, J. E. Turner, G. Dowgier, N. Bogoda, P. Bonfanti, M. Palmarini, A. H. Patel, C. Jolly, G. J. Towers

This study shows that later Omicron subvariants of SARS-CoV-2, such as BA.4 and BA.5, have evolved enhanced innate immune suppression compared to earlier subvariants like BA.1 and BA.2.

bioRxiv · Jul 12, 2022Microbiology

A cell atlas of human thymic development defines T cell repertoire formation

J.-E. Park, R. A. Botting, C. Dominguez Conde, D.-M. Popescu, M. Lavaert, D. J. Kunz, E. Stephenson, R. Ragazzini, E. Tuck, A. L. Wilbrey-Clark, J. R. Ferdinand, S. Webb, D. Maunder, N. Vandamme, K. T. Mahbubani, , S. A. Teichmann

This study creates a cell atlas of the human thymus using scRNA-seq, revealing new cell populations and insights into T-cell development and TCR recombination.

bioRxiv · Jan 28, 2020Immunology