Author

M. Betts

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

C. M. Weight· 2 shared E. Ramos-Sevillano· 2 shared J. A. Guerra-Assuncao· 2 shared J. S. Brown· 2 shared R. S. Heyderman· 2 shared A. Houhou-Ousalah· 1 shared B. Höllbacher· 1 shared C. Jolly· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

C. M. Weight

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Bacterial surface lipoproteins mediate epithelial microinvasion by Streptococcus pneumoniae

J. M. Chan, E. Ramos-Sevillano, M. Betts, H. U. Wilson, C. M. Weight, A. Houhou-Ousalah, G. Pollara, J. S. Brown, R. S. Heyderman

This study investigates how pneumococcal lipoproteins mediate epithelial microinvasion and finds that differential lipoprotein repertoires do not significantly impact microinvasion, suggesting post-translational modifications may be responsible.

bioRxiv · Oct 18, 2023 · PreprintMicrobiology

Essential role of proline synthesis and the one-carbon metabolism pathways for systemic virulence of Streptococcus pneumoniae

E. Ramos Sevillano, G. Ercoli, M. Betts, J. A. Guerra-Assuncao, F. Partridge, V. Silva Entrudo Fernandes, E. Wall, S. Gordon, D. S. Ferreira, R. Heyderman, J. S. Brown

This study shows that one-carbon metabolism is essential for Streptococcus pneumoniae virulence, while proline biosynthesis has a strain-dependent role in systemic infection.

bioRxiv · Aug 3, 2023 · PreprintMicrobiology

Disease-attenuated pneumococcal biosynthesis gene mutants invade the mucosal epithelium and induce innate immunity

C. M. Weight, G. M. Pollara, M. Betts, R. Ragazzini, M. Connor, E. Ramos-Sevillano, J. Reine, M. Whelan, J. A. Guerra-Assuncao, P. Bonfanti, C. Jolly, M. Noursadeghi, D. Ferreira, J. Brown, R. S. Heyderman

This paper shows that disease-attenuated pneumococcal mutants retain epithelial microinvasion but show reduced transmigration and altered inflammatory responses.

bioRxiv · Jun 15, 2023Microbiology

Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy subjects

M. M. Klicznik, P. A. Morawski, B. Höllbacher, S. Varkhande, S. Motley, L. Kuri-Cervantes, E. Goodwin, M. D. Rosenblum, S. A. Long, G. Brachtl, T. Duhen, M. Betts, D. Campbell, I. K. Gratz

The paper identifies human CD4+CD103+ cutaneous resident memory T cells in circulation and shows they can migrate to distant skin sites.

bioRxiv · Mar 14, 2019 · PreprintImmunology