Cardiac Localized Polycystin-2 plays a Functional Role in Natriuretic Peptide Production and its Absence Contributes to Hypertension
B. Elliott, K. M. Marquez-Nogueraz, P. Thuo, E. DiNello, R. M. Knutila, G. E. Fritzmann, M. Willis, A. B. Chapman, Q. Cao, D. Y. Barefield, I. Y. Kuo
This study shows that cardiac polycystin-2 is involved in natriuretic peptide production, and its absence leads to hypertension in ADPKD mice.
bioRxiv · Jan 2, 2024Physiology