Author

R. M. Knutila

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Physiology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

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I. Y. Kuo· 1 shared K. M. Marquez-Nogueras· 1 shared V. Vuchkovska· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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1 shared paperPhysiology

I. Y. Kuo

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1 paper

Recent·Most cited

PhysiologybioRxivPreprintMay 9, 2023

TRiPPing the sensors: The osmosensing pathway of Polycystin 2

K. M. Marquez-Nogueras, R. M. Knutila, V. Vuchkovska, I. Y. Kuo

This study identifies osmolarity as a physiological activator of ER-localized PC2 and shows that MAP4-dependent microtubule stabilization is required for PC2's role in osmosensing and urine concentration.

DOI 10.1101/2023.05.09.540007

mouseproteomics

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