Author

M. Zlei

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Approach:statistical model· 1

Frequent Co-Authors

A. J. van der Sluijs-Gelling· 1 shared A. M. Otte· 1 shared C. J. Halkes· 1 shared E. B. van den Akker· 1 shared E. O. Karakaslar· 1 shared E. Sanchez-Lopez· 1 shared H. Veelken· 1 shared J. F. Severens· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

A. J. van der Sluijs-Gelling

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Autoantibody subclass predominance is not driven by aberrant class switching or impaired B cell development

L. M. Paardekooper, Y. E. Fillie-Grijpma, A. J. van der Sluijs-Gelling, M. Zlei, R. van Doorn, M. H. Vermeer, M. Paunovic, M. J. Titulaer, S. M. van der Maarel, J. J. M. van Dongen, J. J. Verschuuren, M. G. Huijbers

The paper investigates why IgG4 autoantibodies predominate in certain autoimmune diseases and finds that B cell development is normal, suggesting antigen-driven subclass predominance rather than B cell dysfunction.

bioRxiv · Jun 30, 2023Immunology

Single cell guided deconvolution of bulk transcriptomics recapitulates differentiation stages of acute myeloid leukemia and predicts drug response

E. O. Karakaslar, J. F. Severens, E. Sanchez-Lopez, P. A. van Veelen, M. Zlei, J. J. van Dongen, A. M. Otte, C. J. Halkes, P. van Balen, H. Veelken, M. J. Reinders, M. Griffioen, E. B. van den Akker

This study uses single-cell data to deconvolute bulk RNA-seq samples of AML, showing that differentiation stages can be reconstructed and used to predict drug responses like Venetoclax resistance.

bioRxiv · Dec 9, 2022 · PreprintCancer Biology