Cancer BiologybioRxiv
The T Cell Receptor beta Chain Repertoire of Tumor Infiltrating Lymphocytes Improves Neoantigen Prediction and Prioritization
T. M. Q. Pham, T. N. Nguyen, B. Q. T. Nguyen…·L. S. Tran
This paper develops a machine learning model that integrates TCRβ and pHLA binding data to improve neoantigen prioritization in colorectal cancer, showing better performance than existing tools.