MicrobiologybioRxiv
Dual activity of PNGM-1, a metallo-β-lactamase and tRNase Z, pinpoints the evolutionary origin of subclass B3 metallo-β-lactamases
J. H. Lee, M. Takahashi, J. H. Jeon…·S. H. Lee
This paper identifies PNGM-1, a dual-activity enzyme with metallo-β-lactamase and tRNase Z functions, and shows it evolved from tRNase Z, providing insights into the origin of subclass B3 metallo-β-lactamases.
DOI 10.1080/22221751.2019.1692638