Cell BiologybioRxivPreprint
Ca2+-sensor ALG-2 engages ESCRTs to enhance lysosomal membrane resilience to osmotic stress
Wei Chen, Madeline M. Motsinger, Jiaqian Li…·Phyllis I. Hanson
The paper shows that ALG-2, a Ca2+ sensor, recruits ESCRTs to lysosomes to enhance their resilience against osmotic stress-induced rupture.
DOI 10.1101/2024.02.04.578682