Author
RIKEN Center for Integrative Medical Sciences
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Kano Namiki, Wataru Muramatsu, Takahisa Miyao…·Taishin Akiyama
This study investigates the second impact of acute total body irradiation on thymic epithelial cells, finding reduced mTEC frequencies and altered gene expression during the second impact phase.
Kenta Horie, Takahisa Miyao, Yuko Yamagata…·Taishin Akiyama
The paper identifies EHF and ELF3 as key ETS transcription factors that sustain AIRE-primed gene expression in post-AIRE mimetic thymic epithelial cells, ensuring central tolerance.
Nobuko Akiyama, Kenta Horie, Kano Namiki…·Taishin Akiyama
The paper identifies ASCL1 as a key regulator of mTEC function and central tolerance by analyzing single-cell RNA sequencing data from thymoma patients and mouse models.
Mio Hayama, Hiroto Ishii, Maki Miyauchi…·Taishin Akiyama
This study shows that RANKL and CD40L signaling maintain mTEC frequency and TEC progenitor properties in the adult thymus through direct and indirect mechanisms.
Hiroto Ishii, Rin Endo, Sanae Hamanaka…·Taishin Akiyama
This study develops a cryopreservation method for blood cells under ISS constraints, demonstrating viability recovery and subset analysis using flow cytometry.