Cancer BiologyEMBO Molecular MedicinePeer-reviewed
Targeting Pre-existing Club-Like Cells in Prostate Cancer Potentiates Androgen Deprivation Therapy
Manon Baurès, Anne-Sophie Vieira Aleixo, Emeline Pacreau…·Vincent Goffin
This study identifies castration-tolerant Club-like cells in prostate cancer and shows that targeting FOSL1/AP-1 and PIM kinases reduces their progenitor properties and tumor growth.