Cell BiologyThe EMBO JournalPeer-reviewed
Spatial control of the APC/C ensures the rapid degradation of Cyclin B1
Luca Cirillo, Rose Young, Sapthaswaran Veerapathiran…·Jonathon Pines
The paper shows that spatial regulation of the APC/C at mitotic chromosomes enables rapid Cyclin B1 degradation, ensuring proper cell division and genomic stability.