Cell BiologybioRxiv
Endosomal Chemokine Receptor Signalosomes Regulate Central Mechanisms Underlying Cell Migration
H. Hahn, C. Daly, J. Little…·A. R. B. Thomsen
This study shows endosomal chemokine receptor signaling, specifically through CCR7, enhances Rac1 activity and immune T cell chemotaxis by recruiting G protein and β-arrestin.
DOI 10.7554/elife.99373.3